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Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 for the active metabolite N-desmethyldiazepam, which is hydroxylated by CYP3A4 on the active metabolite temazepam.Endured with extreme panic panic assault condition sleeplessness and suicidal thoughts. I'm still using started on 2mg 3 x working day I found a major distinction within days two